Enantioselective Synthesis of 2,2',6-Trisubstituted Biphenyls

DOI: 10.1021/ja00289a023

Source and publish data:

Journal of the American Chemical Society p. 682 - 685 (1985)

Update date:2022-08-05

Topics:

Authors:

Meyers, A. I.

Himmelsbach, Richard J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00289a023

A general procedure is described for the synthesis of chiral biphenyls via nucleophilic aromatic substitution of an o-methoxy group by an aryl Grignard reagent with an oxazoline as a chiral auxiliary.

Full text of DOI:10.1021/ja00289a023

Products guided by the article

Product name:(S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 2'-(tert-butyl-dimethyl-silanyloxymethyl)-6-methoxy-biphenyl-2-ylmethyl ester

Cas No:94293-43-3

R&D Labs maybe for 94293-43-3

LinHai Cina Chemical Co., LTD.

Contact:0576-85580989

Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Tosta Enterprise Co., Ltd.

Contact:+86-134-5286-9121

Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone

Relevant to this article

Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor

Doi:10.1016/j.bmcl.2007.03.035
(2007)
Synthesis of γ-amino acid esters by 1,4-addition of deprotonated α-aminonitriles and α-(alkylideneamino)nitriles to α,β-unsaturated esters

Doi:10.1055/s-2007-965937
(2007)
An efficient optical resolution of nitrogen-centered chiral β-hydroxy-tetraalkylammonium salts via complexation with (R)-BINOL

Doi:10.1016/j.tetlet.2007.04.078
(2007)
"o-Acyl isopeptide method" for peptide synthesis: Synthesis of forty kinds of "o-acyl isodipeptide unit" Boc-Ser/Thr(Fmoc-Xaa)-OH

Doi:10.1039/b702284k
(2007)
Doi:10.1016/0040-4039(76)80092-5
(1976)
Doi:10.1016/S0040-4039(00)93113-7
(1976)

Article Doi