Enantioselective Synthesis of 2,2',6-Trisubstituted Biphenyls

DOI: 10.1021/ja00289a023

Source and publish data:

Journal of the American Chemical Society p. 682 - 685 (1985)

Update date:2022-08-05

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Authors:

Meyers, A. I.

Himmelsbach, Richard J.

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Article abstract of DOI:10.1021/ja00289a023

A general procedure is described for the synthesis of chiral biphenyls via nucleophilic aromatic substitution of an o-methoxy group by an aryl Grignard reagent with an oxazoline as a chiral auxiliary.

Full text of DOI:10.1021/ja00289a023

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