Efficient synthesis of protected l-phosphonophenylalanine (Ppa) derivatives suitable for solid phase peptide synthesis

DOI: 10.1016/j.tetlet.2007.04.027

Source and publish data:

Tetrahedron Letters p. 4051 - 4054 (2007)

Update date:2022-08-05

Topics:

Authors:

Chauhan, Satendra S.

Varshney, Arti

Verma, Bhavana

Pennington, Michael W.

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Article abstract of DOI:10.1016/j.tetlet.2007.04.027

l-Phosphonophenylalanine (Ppa) derivatives were synthesized from l-4-iodophenylalanine and suitably protected phosphites using Michaelis-Arbuzov reaction conditions in the presence of Pd(0) and triethylamine at 70 ± 2 °C.

Full text of DOI:10.1016/j.tetlet.2007.04.027

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