
Chemical and Pharmaceutical Bulletin p. 843 - 853 (1991)
Update date:2022-09-26
Topics:
Harimaya
Gao
Ohkura
Kawamata
Iitaka
Guo
Inayama
Sesquiterpenoids possessing a 7α-isopropyl group, such as curcumol (1a), curdione (2a), curcumalactone (3), and a new epoxy germacrane, (1R,10R)-epoxy-(-)-1,10-dihydrocurdione (5a), were isolated from the essential oil of Curcuma wenyujin. Other related new sesquiterpenes, neocurdione (4) and (1S,10S),(4S,5S)-germacrone-1(10),4-diepoxide (6) were also isolated from this plant. The stereostructures and absolute configurations of these sesquiterpenes were established on the basis of spectroscopic and chemical data as well as X-ray crystallographic analyses.
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