TOTAL SYNTHESIS OF (+/-)-SURUGATOXIN

DOI: 10.1016/S0040-4039(01)81451-9

Source and publish data:

Tetrahedron Letters p. 4407 - 4410 (1984)

Update date:2022-08-04

Topics:

Authors:

Inoue, Shoji

Okada, Kunisuke

Tanino, Hideo

Hashizume, Kiyomatsu

Kakoi, Hisae

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Article abstract of DOI:10.1016/S0040-4039(01)81451-9

Total synthesis of surugatoxin 1, isolated from the toxic Japanese ivory shell (Babylonia japonica), was achieved from 6-bromoisatin by stepwise ring construction involving two key steps: the stereospecific cyclization(9->10) and hydration (17->1).

Full text of DOI:10.1016/S0040-4039(01)81451-9

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