Chemistry Letters p. 1835 - 1836 (1984)
Update date:2022-07-30
Topics:
Kawai, Masao
Ohya, Masashi
Butsugan, Yasuo
Saito, Kazuki
Higashijima, Tsutomu
Diphthaloyl derivative of gramicidin S was subjected to selective N-methylation using CH3I-Ag2O in DMF.Methylation occurred exclusively at ornithine and D-phenylalanine residues affording tetra-N-methylated product in high yield.Removal of the phthaloyl g
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