Chemoenzymatic synthesis of enantiopure 1-phenyl-2-haloethanols and their esters

DOI: 10.3109/10242422.2010.501406

Source and publish data:

Biocatalysis and Biotransformation p. 272 - 278 (2010)

Update date:2022-08-02

Topics: Acylation Regioselectivity Yield NMR spectroscopy Catalyst Enantioselectivity Enantiomeric excess (ee) Recrystallization Hydrolysis Chemoenzymatic synthesis TLC (thin-layer chromatography) HPLC (high-performance liquid chromatography) Protecting group Resolution Workup Halogenation Substrate Kinetic Resolution Chiral Auxiliary Reaction Optimization Enantiopure Esters Polarimetry Solvent system Chiral column

Authors:

Lystvet, Sina Maria

Hoff, Bard Helge

Anthonsen, Thorleif

Jacobsen, Elisabeth Egholm

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3109/10242422.2010.501406

Several secondary haloalcohols have been resolved by esterification catalyzed by lipases A and B from Candida antarctica (CALA and CALB, respectively). Immobilized CALB (Novozym 435) gave better selectivities and faster reaction rates than CALA (Novozyme

Full text of DOI:10.3109/10242422.2010.501406

Products guided by the article

Product name:C₁₇H₁₇BrO₃

Cas No:950759-29-2

R&D Labs maybe for 950759-29-2

HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Xi'an Unique Electronic and Chemical Co., Ltd.

Contact:+86-029-88238008

Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Shanghai better-in Medical Technology Co.,LTD.

Contact:+86-21-38921049

Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
Hubei Honch Pharmaceutical Co.,Ltd

Contact:86-713-7222018

Address:Li Shizhen Pharmaceutical Industry park, Qichun County, Hubei Province,China
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China

Relevant to this article

One-dimensional Salen-type Chain-like lanthanide(III) coordination polymers: Syntheses, crystal structures, and fluorescence properties

Doi:10.1002/zaac.201000366
(2011)
Preparation of penta-azole containing cyclopeptides: challenges in macrocyclization

Doi:10.1016/j.tet.2007.06.103
(2007)
Totally selective reaction of CO₂ with enantiopure amino epoxides under mild reaction conditions. Synthesis and synthetic applications of enantiopure (4R, 1′S)- or (4S,1′S)-4-(1-aminoalkyl)-2-oxo-1,3- dioxolanes

Doi:10.1021/jo070829x
(2007)
Catalyst-free synthesis of quinazolinones by oxidative cyclization under visible light in the absence of additives

Doi:10.1002/jhet.4275
(2021)
Indium- and zinc-mediated Barbier-type allylations of an N,N-(dimethylsulfamoyl)-protected aldimine and subsequent deprotection

Doi:10.1016/j.tetlet.2007.07.167
(2007)
Kinetic resolution of α-acetoxy N-acyl oxazolidinethiones by a chiral O-nucleophilic acyl transfer catalyst

Doi:10.1021/ja053743z
(2005)

Article Doi