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Chemical Baike

Kinetic Resolution

Kinetic resolution is a method for separating enantiomers in a racemic mixture by exploiting the difference in the reaction rates of the two enantiomers. In the context of C-H olefination, one enantiomer reacts preferentially with the reagent, while the other remains unreacted. This process results in one enantiomer of the starting material being transformed into a product, while the other enantiomer remains unchanged. It's crucial to achieve a high degree of selectivity to obtain a highly enantioenriched product.

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