Synthesis and β-lactamase inhibitory properties of 2β-[(acyloxy)methyl]-2-methylpenam-3α-carboxylic acid 1,1-dioxides

DOI: 10.1021/jm00382a025

Source and publish data:

Journal of Medicinal Chemistry p. 518 - 522 (1985)

Update date:2022-08-04

Topics:

Authors:

Gottstein

Haynes Haynes

McGregor

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Article abstract of DOI:10.1021/jm00382a025

p-Nitrobenzyl 2β-[(benzoyloxy)methyl]-2α-methylpenam-3α-carboxylate was prepared by reaction of p-nitrobenzyl 2-[2-oxo-3α-bromo-4-(benzothiazol-2-yldithio)acetidin-1-yl]-2-isopropenyl acetate with silver benzoate in the presence of iodine. The resulting d

Full text of DOI:10.1021/jm00382a025

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