SYNTHESIS OF 1--2-AMINOPROPANE: STUDIES RELATED TO (18)F-LABELED SEROTONIN RECEPTOR LIGANDS

DOI: 10.1016/S0040-4039(00)82391-6

Source and publish data:

Tetrahedron Letters p. 6537 - 6540 (1988)

Update date:2022-08-05

Topics:

Authors:

Gerdes, John M.

Mathis, Chester A.

Shulgin, Alexander T.

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Article abstract of DOI:10.1016/S0040-4039(00)82391-6

Synthesis of the titled 2,5-dimethoxy-4-fluoroalkylamphetamine is reported.The highly functionalized aromatic nucleus of the key fluorination precursor was utimately derived from a low temperature aromatic halogen-lithium exchange reaction followed by alkylation of the resultant anion with ethylene oxide.

Full text of DOI:10.1016/S0040-4039(00)82391-6

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