A practical conversion of an azetidinone to penem: Synthesis of Sch 34343

DOI: 10.1016/S0040-4020(01)90781-1

Source and publish data:

Tetrahedron p. 1175 - 1182 (1992)

Update date:2022-08-04

Topics:

Authors:

Gala Gala

Chiu Chiu

Ganguly Ganguly

Girijavallabhan

Jaret Jaret

Jenkins Jenkins

McCombie

Nyce Nyce

Rosenhouse

Steinman

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)90781-1

A synthesis of penems from azetidinone 1 is described in detail. This synthesis is used to prepare multikilo batches of (5R,6S)-2-[[-(carbamoyloxy)ethyl]thio]-6-[(R)-1-hydroxyethyl]penem-3-carboxylic acid (10), (Sch 34343). It is practical as all chemical

Full text of DOI:10.1016/S0040-4020(01)90781-1

Products guided by the article

Product name:(5R,6S)-3-{[2-(carbamoyloxy)ethyl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Cas No:95415-91-1

R&D Labs maybe for 95415-91-1

ZHEJIANG NHU COMPANY LTD.

Contact:86-575-86132822，86-575-86085355

Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.
Chengdu Biopurify Phytochemicals Ltd.

website:http://www.phytopurify.com

Contact:+86-28-82633397

Address:2F,No.11 Building,No.388 Rongtaidadao CNSTP,Wenjiang Zone,Chengdu,Sichuan, China
Shanghai Balmxy Pharmaceutical Co., Ltd

Contact:0086-21-24206007

Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China
Hefei Highzone Fine Chemical S&T CO.,LTD

Contact:86-0551-63663560

Address:room 1801 NO. 24 Shuguang RD.
Dongying J&M Chemical Co., Ltd,

Contact:546-8551108

Address:Room 1219, Zisheng Mansion, Zibo Road, Dongying, Shandong, China

Relevant to this article

Succinimidinium hydrogensulfate ([H-Suc]HSO₄) as a new, green and efficient ionic liquid catalyst for the synthesis of tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-one, 1-(benzothiazolylamino)phenylmethyl-2-naphthol, 1, 8-dioxo-octahydroxanthen

Doi:10.1007/s13738-016-0822-1
(2016)
Facile access to pentavalent uranium organometallics: One-electron oxidation of uranium(IV) imido complexes with copper(I) salts

Doi:10.1021/ja074889w
(2007)
Amino-caprolactam derivatives as γ-secretase inhibitors

Doi:10.1016/j.bmcl.2007.08.047
(2007)
Interaction of 1-tert-perfluorobutyl-3,3-di(perfluoromethyl)-2-aziridinone with weak nucleophiles

Doi:10.1007/BF00697089
(1993)
Synthesis of new series of 4, 5-dihydroisoxazole-5-carboxylate derivatives for the study of their liquid crystalline properties

Doi:10.1007/s12039-016-1114-0
(2016)
7α-Substituted Derivatives of Androstenedione as Inhibitors of Estrogen Biosynthesis

Doi:10.1021/jm00383a019
(1985)

Article Doi