Journal of the Chemical Society. Chemical communications p. 1381 - 1382 (1984)
Update date:2022-07-31
Topics:
Godoy, Jose
Ley, Steven V.
Lygo, Barry
A route to enantiomerically pure 1,7-dioxaspiro<5.5>undecanes as important building blocks for milbemycin/avermectin synthesis is described, involving the Wittig reaction of a substituted cyclic ether with aldehydes, followed by spiroacetalisation.
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