SHORT CHAIN PEPTIDE INHIBITORS OF HUMAN RENIN

DOI: 10.1246/cl.1985.1041

Source and publish data:

Chemistry Letters p. 1041 - 1044 (1985)

Update date:2022-08-04

Topics:

Authors:

Matsueda, Rei

Yabe, Yuichiro

Kogen, Hiroshi

Higashida, Susumu

Koike, Hiroyuki

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1985.1041

The phenylalanine residue in the C-terminal sequence of angiotensin II was found to be important for the design of renin inhibitors. 1-Naphthylalanine(Nal(1))-containing tripeptide analogues such as benzyloxycarbonyl-Na1(1)-His-Leucinal (ES-188) and benzyloxycarbonyl-Nal(1)-His-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid (Statine)⁵ 2(S)-methylbuthylamide (ES-254) showed high potency and specificity to human renin.

Full text of DOI:10.1246/cl.1985.1041

Products guided by the article

Product name:benzyloxycarbonyl-L-<3-(1-naphthyl)>alanyl-L-histidine hydrazide

Cas No:96386-78-6

R&D Labs maybe for 96386-78-6

miao tie sheng

Contact:0311-13263231263

Address:jian hua street,Shijiazhuang City, China
Luojiang Chenming Biological Products Co

Contact:+86 15000297032

Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37
hangzhou verychem science and technology co.ltd

website:http://www.verypharm.com

Contact:+86-571-88162785; 88162786

Address:F1502, 753 Shenhua road, Hangzhou, China

Relevant to this article

Doi:10.1021/jo01059a018
(1962)
A STUDY OF NITROGEN- AND OXYGEN-CONTAINING HETEROCYCLES. 42. PYRIMIDO<4,5-b>- AND PYRIDO<2,3-b>-1,4-BENZOXAZEPINES

Doi:10.1007/BF00505911
(1985)
Total synthesis of amauromine

Doi:10.1016/S0040-4039(00)61945-7
(1985)
(+)-Methyl (1 R, 2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: Stereochemistry and pharmacological properties

Doi:10.1021/acs.jmedchem.7b01584
(2018)
Structure of the Alkali-Labile Product Formed during Iron(II)-Bleomycin-Mediated DNA Strand Scission

Doi:10.1021/ja00299a072
(1985)
Unprecedented outcome of base-promoted neber rearrangement of O-Mesyloxime of 2-aryl-1,2,3,4-tetrahydro-1-methylsul fonyl-4-quinolone-synthesis of 4-amino-2-arylquinolines

Doi:10.1080/10426500008076551
(2000)

Article Doi