Nucleosides. 134. 3'-Amino-3'-deoxy-β-D-hexopyranosyl Nucleosides. 8. Synthesis of 2,3'-Imino Nucleosides by Solvolysis of 2'-O-Mesylglucosyluracil Derivatives

Article abstract of DOI:10.1021/jo00215a013

Treatment of 1-(3'-acetamido-3'-deoxy-2',4'-di-O-mesyl-β-D-glucopyranosyl)uracil (1) with sodium acetate in aqueous methylcellosolve afforded 1-(3'-amino-3'-deoxy-β-D-talopyranosyl)uracil and 2,3'-imino-1-(3'-amino-3'-deoxy-β-D-talopyranosyl)isocytosine i