TETRA-ACETYLENIC METABOLITES FROM MYCENA VIRIDIMARGINATA

Article abstract of DOI:10.1016/S0031-9422(00)80765-7

Key Word Index - Mycena viridimarginata; Basidiomycetes; acetylenic compounds; tetraynamide; tetrayne lactone; chromophores of polyynamides. - The structures of two new acetylenic compounds fro Mycena viridimarginata were elucidated by spectroscopic methods and some chemical transformations.The major metabolite was 10-hydroxyundeca-2,4,6,8-tetraynamide and the minor one was 3,4,13-trihydroxytetradeca-5,7,9,11-tetraynoic acid γ-lactone.Another compound, methyl-3,4,13-trihydroxytetradeca-5,7,9,11-tetraynoate, was found to be an artifact from the γ-lactone produced on the Sephadex LH-20 column.Furthermore, model compounds were prepared to establish the chromophoric system of the major metabolite.