An Improved Method for Synthesis of L-Homoglutamic Acid via Epsilon-N-deamination of L-Lysine Derivative

DOI: 10.1246/bcsj.58.1171

Source and publish data:

Bulletin of the Chemical Society of Japan p. 1171 - 1173 (1985)

Update date:2022-08-05

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Authors:

Kondo, Michio

Miyazaki, Koujiro

Kodama, Hiroaki

Horimoto, Hideaki

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Article abstract of DOI:10.1246/bcsj.58.1171

A convenient procedure to prepare L-homoglutamic acid (L-2-aminoadipic acid; L-Aad) is described.Chlorination of ε-amino group in acetyl-L-lysine ethyl ester with t-butyl hypochlorite (t-BuOCl) followed by dehydrochlorination with pyridine gave ethyl 5-cy

Full text of DOI:10.1246/bcsj.58.1171

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