Low Temperature Free-Radical Reactions Initiated with tert-Butyl p-Benzoylperbenzoate. Selective Acyl Radical Additions to Substituted Olefins

Article abstract of DOI:10.1021/jo00219a015

Competition experiments involving acyl radical additions to simple and electron-deficient olefins showed a definite preference for acylation of the latter olefin.This selectivity was significantly enhanced by using low temperature initiation with tert-butyl p-benzoylperbenzoate (1), which allows selective initiation of free-radical cyclization reactions that have synthetic importance.