Sulfur-interrupted 8-amino side chain analogues of 4-methyl-5-[m-(trifluoromethyl)phenoxy]primaquine as potential antimalarial agents

DOI: 10.1021/jm00150a035

Source and publish data:

Journal of Medicinal Chemistry p. 1959 - 1962 (1985)

Update date:2022-08-04

Topics:

Authors:

Carroll Carroll

Berrang Berrang

Linn Linn

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00150a035

Two isomeric sulfur-interrupted 8-amino side chain analogues of 4-methyl-5-[m-(trifluoromethyl)phenoxy]primaquine (2) were prepared and tested for antimalarial activity. The compounds were evaluated for blood schizonticidal activity aginst Plasmodium berg

Full text of DOI:10.1021/jm00150a035

Products guided by the article

Product name:8-((5'-amino-2'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinoline

Cas No:98586-87-9

R&D Labs maybe for 98586-87-9

BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès
Chengda Pharmaceuticals Co., Ltd.

Contact:+86-573-84601188

Address:hengshan Road 5# in Jiashan, zhejiang
MTT Pharma & Bio-technology Co.,Ltd(expird)

Contact:+86-21-58407925

Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China
Weifang Jahwa Chemical Co.,Ltd

Contact:0086-536-8897731,8897730

Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
Taizhou Chemedir Biopharm-tech Co., Ltd

Contact:+86 523 86200218

Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China

Relevant to this article

Synthesis and mass spectra of 4-O-acetyl-1,5-anhydro-2,3,6-tri-O-(methoxycarbonylmethyl)-D-glucitol and the positional isomers of 4-O-acetyl-1,5-anhydro-di-O-(methoxycarbonylmethyl)-O-methyl-D-glucitol and 4-O-acetyl-1,5-anhydro-O-(methoxycarbonylmethyl)-

Doi:10.1016/0008-6215(91)84145-5
(1991)
Carbenoid entry into trifluoromethylated molecules: Preparation of functionalized CF₃-containing γ, δ-unsaturated carboxylic esters by rhodium-catalyzed reaction of ethyl 3,3,3-trifluoro-2-diazo-propionate with allylic sulfides and their furthe

Doi:10.1016/S0040-4020(01)96907-8
(1991)
Mixed-metal lanthanide-iron triple-decker complexes with a cyclo-P ₅ building block

Doi:10.1002/anie.201102748
(2011)
Asymmetric Bronsted acid catalyzed carbonyl activation - Organocatalytic domino electrocyclization-halogenation reaction

Doi:10.1039/c1cc15289k
(2011)
Comparison of convenient alternative synthetic approaches to 4-[(3-tert-butyldimethylsilyloxy)phenyl]-4-methoxyspiro[1,2-dioxetane-3, 2′-adamantane]

Doi:10.1055/s-2006-942357
(2006)
Carbonyldiimidazole (CDI) mediated synthesis of N^α- protected amino acid azides: Application to the one-pot preparation of ureidopeptides

Doi:10.2174/092986611797200922
(2011)

Article Doi