Synthesis and investigation of the β-adrenoceptor agonist and platelet antiaggregatory properties of 1,7,8-trisubstituted 2,3,4,5-tetrahydro-1H-2-benzazepine analogues of trimetoquinol

Article abstract of DOI:10.1021/jm00152a003

The synthesis and biological evaluation of 7,8-dihydroxy (2) and 7,8-methylenedioxy (3) analogues of 1-[(3,4,5-trimethoxyphenyl)methyl]-2,3,4,5-tetrahydro-1H-2-benzazepine on β-adrenoceptor systems and human platelets were undertaken and compared with tri