Synthesis and hypolipidemic activities of 5-thienyl-4-oxazoleacetic acid derivatives

DOI: 10.1021/jm00153a006

Source and publish data:

Journal of Medicinal Chemistry p. 333 - 341 (1986)

Update date:2022-09-26

Topics:

Authors:

Moriya Moriya

Takabe Takabe

Maeda Maeda

Matsumoto

Takashima

Takeyama

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Article abstract of DOI:10.1021/jm00153a006

A series of 2,5-disubstituted 4-oxazoleacetic acid derivatives was synthesized and evaluated for hypolipidemic activity. Among them, those with a thienyl group at C-5 of the oxazole ring exerted highly potent hypolipidemic effects in rats. 2-(4-Fluorophen

Full text of DOI:10.1021/jm00153a006

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