Synthesis and hypolipidemic activities of 5-thienyl-4-oxazoleacetic acid derivatives

DOI: 10.1021/jm00153a006

Source and publish data:

Journal of Medicinal Chemistry p. 333 - 341 (1986)

Update date:2022-09-26

Topics:

Authors:

Moriya Moriya

Takabe Takabe

Maeda Maeda

Matsumoto

Takashima

Takeyama

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00153a006

A series of 2,5-disubstituted 4-oxazoleacetic acid derivatives was synthesized and evaluated for hypolipidemic activity. Among them, those with a thienyl group at C-5 of the oxazole ring exerted highly potent hypolipidemic effects in rats. 2-(4-Fluorophen

Full text of DOI:10.1021/jm00153a006

Products guided by the article

Product name:3-Thiophenecarboxamide, N-[2-(4-fluorophenyl)-2-oxoethyl]-

Cas No:99923-42-9

R&D Labs maybe for 99923-42-9

Changzhou Hopschain Chemical Co.,Ltd

website:http://www.hopschem.cn/products.html

Contact:86-519-85528066

Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Changzhou Qidi Chemical Co., Ltd

website:http://www.czqdhg.com/

Contact:86-519-83382137

Address:128-1-16# HuaYuan Street,Hutang Town,Wujin District,Changzhou City,P.R.China.
HEZE KINGVOLT CHEMICAL CO., LTD

Contact:86-573-82118911

Address:Juancheng Industry Park
Suzhou BEC Fine Chemicals Co., Ltd.

website:http://www.bek.com.cn

Contact:0512-68095917　 18913193865

Address:6, Jin Shan Road, Suzhou New District, 215011 China Suzhou Nations Pharmaceutical Innovation Center Inside
Huangshan Violet Biological Technology Co., Ltd

Contact:+86-559-2335676

Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China

Relevant to this article

Enantioselective Aza-Henry reaction with an N-sulfinyl urea organocatalyst

Doi:10.1021/ja075653v
(2007)
Palladium-catalysed N-annulation routes to indoles: The synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1

Doi:10.1039/b712227f
(2007)
Ionothermal syntheses of six three-dimensional zinc metal-organic frameworks with 1-alkyl-3-methylimidazolium bromide ionic liquids as solvents

Doi:10.1021/ic701393w
(2007)
Palladium(II) pyrazolin-4-ylidenes: Remote N-heterocyclic carbene complexes and their catalytic application in aqueous Suzuki-Miyaura coupling

Doi:10.1021/om7009107
(2007)
Multi-step redox systems with NIR-fluorescence based on 4H-imidazoles

Doi:10.3390/12040723
(2007)
Doi:10.1039/jr9620003963
(1962)

Article Doi