THE SYNTHESIS OF AN ACTIVE DERIVATIVE OF CYCLOMALTOHEPTAOSE FOR THE HYDROLYSIS OF ESTERS AND THE FORMATION OF AMIDE BONDS

Article abstract of DOI:10.1016/0008-6215(89)85171-7

The synthesis is described of a derivative of cyclomaltoheptaose (β-cyclodextrin) to which the tripeptide Ser-His-Asp, the catalytic triad found in chymotrypsin, has been coupled.The derivative enhanced the rates of hydrolysis of activated esters, as meas