Tetrahedron Letters p. 1543 - 1546 (1983)
Update date:2022-08-29
Topics:
Fujisawa, Tamotsu
Mori, Toshiki
Tsuge, Shoichi
Sato, Toshio
A new method for the direct conversion of carboxylic acids to aldehydes using N,N-dimethylchloromethyleniminium chloride and tri-t-butoxyaluminum hydride was established.This method provides a convenient way for the chemoselective reduction of carboxylic acids even with such a functional group as halide, ester, nitrile, olefin and ketone.
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