Tetrahedron Letters p. 5465 - 5468 (1998)
Update date:2022-08-30
Topics:
Andrus, Merritt B.
Li, Wenki
Keyes, Robert F.
Mixed acyclic imides are assembled using amide anions and pentafluorophenyl esters reacted in THF at low temperature. Sodium hexamethyldisilazide deprotonates lactam 4 followed by addition of pentafluorophenyl (PFP) esters to give imides in high yield (85
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