(2S,5S,8S,11S)-1-ACETYL-1,4-DIAZA-3-KETO-5-CARBOXY-10-THIA-TRICYCLO-(2.8.04,8)-TRIDECANE, 1 SYNTHESIS OF PROLYL-PROLINE-DERIVED, PEPTIDE-FUNCTIONALIZED TEMPLATES FOR α-HELIX FORMATION

DOI: 10.1016/S0040-4039(00)80644-9

Source and publish data:

Tetrahedron Letters p. 4931 - 4934 (1988)

Update date:2022-08-11

Topics:

Authors:

Kemp, D. S.

Curran, Timothy P.

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Article abstract of DOI:10.1016/S0040-4039(00)80644-9

A convergent synthesis is reported for the title compound 1 (X = OH) from L-4-hydroxyproline and (2S,5S)-trans-1-benzyl-2,5-dicarbomethoxypyrrolidine.The peptides αTemp-(L-Ala)n-OMe (n = 1,2,3,4) and αTemp-L-Ala-L-Phe-L-Lys(ε-Boc)-L-Lys(ε-Boc)-NHMe (αTemp

Full text of DOI:10.1016/S0040-4039(00)80644-9

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