
Tetrahedron Letters p. 4093 - 4096 (1999)
Update date:2022-08-11
Topics:
Le Sann, Christine
Simpson, Thomas J.
Smith, David I.
Watts, Paul
Willis, Christine L.
A convenient and efficient route for the enantioselective synthesis of functionalised β-hydroxy N-acetylcysteamine thioesters is described. The route allows the facile incorporation of vicinal 13C labelling to produce intermediates required for biosynthetic studies on a wide range of polyketide metabolites, e.g. 6-MSA, monocerin, colletodiol and strobilurins.
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