Bioorganic and Medicinal Chemistry Letters p. 1089 - 1092 (1998)
Update date:2022-08-11
Topics:
Xu, Wei
Mohan, Raju
Morrissey, Michael M.
A convenient solution-phase method for N-alkylation reactions of weakly acidic heterocycles employing polymer supported super base PBEMP is described. By using this method, multiple-step and chemoselective N- alkylation sequences can be carried out in a one-pot process.
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