A new method for the preparation of β-hydroxy nitriles; Transformation of 3-bromo-2-isoxazolines to β-hydroxy nitriles by treatment of alkanethiolates

Article abstract of DOI:10.1080/00397919408011747

3-Bromo-2-isoxazolines are transformed to β-hydroxy nitriles in good yields by treatment with alkanethiolates under a very mild condition.

Full text of DOI:10.1080/00397919408011747

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A New Method for the
Preparation of β-Hydroxy
Nitriles: Transformation of 3-
Bromo-2-isoxazolines to β-
Hydroxy Nitriles by Treatment
of Alkanethiolates
Min Hyo Seo a , Youn Young Lee a & Yang Mo Goo b
a Department of Chemistry
b Department of Pharmacy , Seoul National
University , Seoul, 151-742, Korea
Published online: 23 Sep 2006.
To cite this article: Min Hyo Seo , Youn Young Lee & Yang Mo Goo (1994) A New
Method for the Preparation of β-Hydroxy Nitriles: Transformation of 3-Bromo-2-
isoxazolines to β-Hydroxy Nitriles by Treatment of Alkanethiolates, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 24:10, 1433-1439, DOI: 10.1080/00397919408011747
To link to this article: http://dx.doi.org/10.1080/00397919408011747
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