A New Enzymatic Synthesis of (R)-γ-Chloro-β-Hydroxybutyronitrile

DOI: 10.1016/S0040-4020(01)89297-8

Source and publish data:

Tetrahedron p. 11821 - 11826 (1994)

Update date:2022-08-11

Topics:

Authors:

Nakamura, Tetsuji

Nagasawa, Toru

Yu, Fujio

Watanabe, Ichiro

Yamada, Hideaki

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Article abstract of DOI:10.1016/S0040-4020(01)89297-8

A new enzymatic synthesis of (R)-γ-chloro-β-hydroxybutyronitrile from epichlorohydrin or 1,3-dichloro-2-propanol using halohydrin hydrogen-halide-lyase purified from a recombinant Escherichia coli that carried the enzyme gene of Corynebacterium sp. strain N1074 was described.

Full text of DOI:10.1016/S0040-4020(01)89297-8

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