Catalytic asymmetric induction part 2. Chiral tricarbonyl (η6 arene) chromium (O) complexes as enantioselective catalysts

Article abstract of DOI:10.1016/S0957-4166(00)82346-0

A chiral metallocyclic Lewis acid based catalyst system derived from norephedrine is reported. A key stereodirective element emanates from a tricarbonyl chromium (O) group complexed to the aryl ring. The catalysts mediate the addition of dialkyl zinc species to a variety of aldehydes with high enantioselectivity.