Journal of the Chemical Society. Perkin transactions I p. 1355 - 1362 (1985)
Update date:2022-08-29
Topics:
Gani, David
Young, Douglas W.
A mammalian enzyme system has been used to study the stereochemistry of the catabolism of the pyrimidine uracil (1) to the amino acid β-alanine (4).Use of <5-(2)H>- and <6-(2)H>- uracils and of (2)H2O in the incubations yielded sterospecifically deuteriated samples of β-alanine.Assays, involving total synthesis of samples of β-alanine unambigously labelled with deuterium in each of the four C-H bonds have shown that, in the first step in the catabolic process, uracil is reduced by dihydrouracil dehydrogenase with overall anti addition of hydrogen, at the si face at C-6 and the si face at C-5.
View MoreHangzhou Showland Technology Co., Ltd.
Contact:86-571-88920516
Address:ROOM2118,NO.553,WENSAN ROAD,HANGZHOU,CHINA
Hangzhou Neway Chemicals Co., Ltd.
Contact:+86-571-85095566
Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Weifang Dongxing Chitosan Factory
website:http://dxchitosan.lookchem.com/
Contact:13475651157
Address:Weifang city ,shandong province
Hangzhou Deli Chemical Co.,Ltd.
website:http://www.dlchemical.com
Contact:86 571 28006267
Address:Tangxi Industrial Area, Yuhang District, Hangzhou
Contact:410-273-7300; 800-221-3953
Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Doi:10.1016/j.jorganchem.2007.07.003
(2007)Doi:10.1002/jccs.199900078
(1999)Doi:10.3390/molecules17043957
(2012)Doi:10.1002/jhet.786
(2012)Doi:10.1016/S0022-328X(00)96185-0
(1980)Doi:10.1039/j39670000128
(1967)
