Synthesis of sterically hindered amine containing azide via chemoselective hydride reduction

Article abstract of DOI:10.1080/00397919808006875

The chemoselective reduction of an ester in the presence of an azido group by LiCl/NaBH₄ is described. A sterically hindered secondary amine containing an azido group is synthesized by this method.

Full text of DOI:10.1080/00397919808006875

This article was downloaded by: [University of California Santa Cruz]
On: 07 March 2015, At: 23:30
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
Synthesis of Sterically
Hindered Amine Containing
Azide via Chemoselective
Hydride Reduction
a
Hwa-Ok Kim
a
Molecumetics Ltd. , 2023 120th Ave. N.E. Suite
400, Bellevue, WA, 98005-2199
Published online: 22 Aug 2006.
To cite this article: Hwa-Ok Kim (1998) Synthesis of Sterically Hindered Amine
Containing Azide via Chemoselective Hydride Reduction, Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry,
28:9, 1713-1720, DOI: 10.1080/00397919808006875
To link to this article: http://dx.doi.org/10.1080/00397919808006875
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,
or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and
are not the views of or endorsed by Taylor & Francis. The accuracy of the
Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any

losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or
indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions