Tetrahedron Letters p. 3659 - 3660 (1986)
Update date:2022-08-25
Topics:
Fujita, Makoto
Hiyama, Tamejiro
Treatment of 1,1-difluoro-2-halo-1-alken-3-ols with various halogenating reagents gave (Z)-1,1-difluoro-1,2-dihalo-2-alkenes under high regio- and stereocontrol.This transformation was applied to the construction of C-3 side chain CH=C(X)CF2X' (X, X' = F
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