Synthesis of C-5'-nor-dideoxycarbanucleosides structurally related to neplanocin C

Article abstract of DOI:10.1080/07328319908044877

Purine carbanucleosides built on a 6-oxabicyclo[3.1.0]hexane template were synthesized from readily available 2-cyclopentenone employing a Mitsunobu reaction to incorporate the base onto the carbocyclic ring. Both adenosine and guanosine analogues exhibited moderate antiviral activity.

Full text of DOI:10.1080/07328319908044877

Nucleosides and Nucleotides
ISSN: 0732-8311 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/lncn19
Synthesis of c-5′-nor-Dideoxycarbanucleosides
Structurally Related to Neplanocin C
Maria J. Comin , Carlos A. Pujol , Elsa B. Damonte & Juan B. Rodriguez
To cite this article: Maria J. Comin , Carlos A. Pujol , Elsa B. Damonte & Juan B. Rodriguez
(1999) Synthesis of c-5′-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C,
Nucleosides and Nucleotides, 18:10, 2219-2231, DOI: 10.1080/07328319908044877
To link to this article: http://dx.doi.org/10.1080/07328319908044877
Published online: 04 Oct 2006.
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Date: 07 May 2016, At: 21:12