Preparative Flow Techniques; 1. Low-Temperature Organometallic Reactions: Synthesis of Ethyl 2,2-Difluoro-4-pentenoate

DOI: 10.1055/s-1988-27608

Source and publish data:

Synthesis p. 469 - 470 (1988)

Update date:2022-08-10

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Authors:

Kolb, Michael

Gerhart, Fritz

Francois, Jean-Paul

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Article abstract of DOI:10.1055/s-1988-27608

A convenient preparation of the synthetically useful ethyl 2,2-difluoro-4-pentenoate using the low-temperature flow technique is described.The method is suitable for small-scale as well as for large-scale application.

Full text of DOI:10.1055/s-1988-27608

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