Tetrahedron Letters p. 3645 - 3648 (1989)
Update date:2022-08-17
Topics:
Stille, J.K.
Sweet, Mark P.
The palladium catalyzed coupling of (S)-E-1-tributylstannyl-1-octen-3-ol (3) with 2-(6-carbethoxyhexyl)-3-iodo-2-cyclopenten-1-one gave a 70percent yield of the (S)-ethyl ester of PGB1.Coriolic acid was synthesized in 75percent yield by coupling 3 with Z-10-iododecenoic acid, demonstrating the tolerance of this coupling reaction to the carboxylic acid function.
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(2019)