The Enantioface-Differentiating Hydrogenation of the C=O Double Bond with Asymmetrically Modified Raney Nickel. XXXIX. Repeated Uses of the Catalyst in the Hydrogenation of 2-Alkanones

Article abstract of DOI:10.1246/bcsj.60.1277

The durability of tartaric acid-sodium bromide-modified Raney nickel in the hydrogenation of 2-octanone was investigated.A remarkable lowering of the optical yield was observed in the repeated use of the catalyst.A lack of sodium ions in the reaction system was found to be the origin of this phenomenon.The addition of sodium ions to the reaction mixture was useful for attaining high optical yields in the repeated uses of the catalyst.