Highly stereocontrolled synthesis of a novel tribactam by reaction of an ester enolate with a N-trimethylsilylimine

Article abstract of DOI:10.1016/0040-4039(96)00394-2

The azetidinone 14, a key intermediate in the synthesis of novel tribactam antibiotics (e.g. 2) was obtained via condensation of an ester enolate with a N-trimethylsilylimine.