
Chemistry of Heterocyclic Compounds p. 775 - 778 (2000)
Update date:2022-08-11
Topics:
Lebedev
Leite
Fleisher
Stonkus
The relative stability of 2-hydroxytetrahydrofuran and the tautomeric 4-hydroxybutanal was determined by the semi-empirical AM1 method. It was concluded that the cyclic tautomer predominates in the gas phase at 25°C. Vapor-phase dehydration of 2-hydroxytetrahydrofuran in the presence of porcelain and silica gel L leads to a quantitative yield of 2,3-dihydrofuran.
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