Journal of Organic Chemistry p. 3706 - 3708 (1987)
Update date:2022-09-26
Topics: Total synthesis Work-Up Convergent Synthesis Reaction flask
Martin, Stephen F.
Dappen, Michael S.
Dupre, Brian
Murphy, Christopher J.
A highly convergent, enantioselective total synthesis of (+)-phyllanthocin (1), the aglycone of the antineoplastic agent phyllanthoside (2), has been achieved by employing a novel strategy that features a stereo- and regioselective dipolar cycloaddition o
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