Palladium(0)-catalyzed phenylation of imidazo[4,5-b]pyridines

Article abstract of DOI:10.1002/jhet.5570320214

The tetrakis(triphenylphosphine)palladium(0)-catalyzed coupling of benzeneboronic acid with 2-chloro, 6-bromo and 6-bromo-2-chloro derivatives of 1- and 3-methylimidazo[4,5-b]pyridines to novel 2-phenyl-, 6-phenyl- and 2,6-diphenylimidazo[4,5-b]pyridines is described. The phenylation of imidazo[4,5-b]pyridines containing labile hydrogens was not successful.