Cleavage of 2-Phenyl-1,3-dioxolanes and Benzyl Ethers by Catalytic Transfer Hydrogenation

Article abstract of DOI:10.1055/s-1986-31597

The selective deprotection of 2-phenyl-1,3-dioxolane derivatives and benzyl ethers of carbohydrates can be accomplished by catalytic transfer hydrogenation using hydrazine hydrate as hydrogen donor and 10percent palladium on carbon as catalyst.Under these conditions, 2-phenyl-1,3-dioxan and 2-alkyl substituted 1,3-dioxolane moieties remain unaffected.The proposed method is effective and the deprotected compounds are obtained in high yields.