Synthesis of (-)-Syringolides 1 and 2

Article abstract of DOI:10.1016/0040-4020(95)00488-T

The enatioselective synthesis of (-)-syringolides 1 and 2 which were isolated as specific elicitors produced by Pseudomonas syringae pv. tomato was accomplished in 11 steps from diethyl D-tartrate.The specific rotations of synthetic samples were in good accord with those of the natural syringolides, and synthetic syringolide 2 showed almost the same biological activity as that of natural syringolide 2.