Asymmetric Reduction of ortho-Substituted Benzophenones with B-Chlorodiisopinocampheylborane: A Convenient Synthesis of Enantiomerically Enriched Benzhydrols

DOI: 10.1016/0040-4039(95)00609-G

Source and publish data:

Tetrahedron Letters p. 3797 - 3800 (1995)

Update date:2022-08-11

Topics:

Authors:

Shieh, Wen-Chung

Cantrell, William R.

Carlson, John A.

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Article abstract of DOI:10.1016/0040-4039(95)00609-G

A very efficient synthesis of chiral benzhydrols from ortho-substituted benzophenones is described which presumably utilizes a heteroatom-directed, intramolecular asymmetric reduction of ketones with B-chlorodiisopinocampheylborane.

Full text of DOI:10.1016/0040-4039(95)00609-G

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