TERPENOID AND OTHER EXTRACTIVES OF WESTERN WHITE PINE BARK

Article abstract of DOI:10.1016/0031-9422(80)83068-8

A detailed chemical analysis of the benzene extract of western white pine bark was conducted.The extract consisted of 13percent phlobaphenes, 18percent strong acids, 21percent polar weak acids, 6.5percent fatty acids, 9.5percent resin acids, and 32percent neutrals.The fatty acids consisted mainly of C_20:O, C_22:O, and C_24:O acids.The resin acids were identified as: isopimaric, anticopalic, dehydroabietic, sandaracopimaric, abietic, 6,8,11,13-abietatetraen-18-oic and pimaric acids.The neutrals on saponification gave fatty acids, sterols, wax alcohols, nonsaponifiables, and other components.The esterified fatty acids consisted primarily of the C_16:O, C_18:O, C_20:O and C_24:O acids.The sterols included major amounts of sitosterol, campesterol, and stigmasterol, and traces of cholesterol.Over 70 individuel compounds were isolated and identified from the nonsaponifiables.These included borneol, sesquiterpenes, diterpenes, steroidal ketones, as well as lanostane and serratane triterpenes.The characterization of 12 new natural products or natural products isolated for the first time from Pinus species is reported. - Key Word Index: Pinus monticola; Pinaceae; western white pine; bark extractives; resin acids; triterpenes; sterols; fatty acids.