Tetrahedron Letters p. 7983 - 7986 (1998)
Update date:2022-08-17
Topics:
Dunstan, Andrew R.
Weber, Hans-Peter
Rihs, Grety
Widmer, Hans
Dziadulewicz, Edward K.
Novel tri-substituted 1,2,4-triazoles are synthesized via complementary, regiospecific routes as part of a lead finding exercise. A key feature of one of the syntheses is recognition of an intrinsic regioselectivity toward deprotonation in the 1-phenylguanazole substrate.
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