Tetrahedron Letters p. 6557 - 6560 (1988)
Update date:2022-08-11
Topics:
Rounds, William D.
Eaton, Jefferson T.
Urbanowicz, John H.
Gribble, Gordon W.
The reaction of nitriles with tetrafluorophthalic or tetrachlorophthalic acid gives carboxylic acids in good yield.The reaction is chemoselective in that the nitrile functionality can be hydrolyzed in the presence of ester groups.
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