Chiral oxazaborolidines bearing a 1- or 2-naphthylmethyl group as catalysts for the enantioselective borane reduction of ketones: Experimental and quantum chemical calculations

Article abstract of DOI:10.1016/S0957-4166(98)00079-2

Two new catalysts for the enantioselective reduction of ketones, chiral 1,3,2-oxazaborolidines substituted at carbon 4 by a 1- or 2-naphthylmethyl group, have been prepared from the related amino alcohols, by treatment with borane in tetrahydrofuran, and