Asymmetric reduction of α-keto acetals with potassium 9-O-(1,2- isopropylidene-5-deoxy-D-xylofuranosyl)-9-boratabicyclo[3.3.1] nonane. Enantioselective synthesis of α-hydroxy acetals with high optical purities

Article abstract of DOI:10.1016/0957-4166(94)80142-8

Asymmetric reduction of α-keto acetals with a chiral borohydride, potassiun 9-O-(1,2-isopropylidene-5-deoxy-α-D-xylofuranosyl)-9- boratabicyclo[3.3.1]nonane in THF at -78°C provided the corresponding α- hydroxy acetals with 87-99% ee.