A convenient and versatile method for the synthesis of protected guanidines

Article abstract of DOI:10.1080/00397910008087443

Aromatic, aliphatic and sterically hindered amines react smoothly with commercially available N, N'-bis-BOC-S-methylisothiourea 2 in the presence of mercury chloride to give the protected guanidine in good yield. It is particularly noteworthy that 2 can a

Full text of DOI:10.1080/00397910008087443

This article was downloaded by: [Umeå University Library]
On: 20 November 2014, At: 19:21
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
A Convenient and Versatile
Method for the Synthesis of
Protected Guanidines
a
a
Zhao-Xia Guo , Andrew N. Cammidge & David C.
b
Horwell
a
School of Chemical Sciences , University of East
Anglia , Norwich, NR4 7TJ, UK
b
Parke-Davis Neuroscience Research Centre,
Cambridge University Forvie Site , Robinson Way,
Cambridge, CB2 2QB, UK
Published online: 04 Dec 2007.
To cite this article: Zhao-Xia Guo , Andrew N. Cammidge & David C. Horwell (2000) A
Convenient and Versatile Method for the Synthesis of Protected Guanidines, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 30:16, 2933-2943, DOI: 10.1080/00397910008087443
To link to this article: http://dx.doi.org/10.1080/00397910008087443
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,
or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and

are not the views of or endorsed by Taylor & Francis. The accuracy of the
Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any
losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or
indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions