Asymmetric Reduction of Aromatic Ketones with Reagents Prepared from NaBH4 and ZnCl2 in the Presence of 1,2 : 5,6-Di-O-isopropylidene-α-D-glucofuranose

Article abstract of DOI:10.1246/bcsj.54.1424

Asymmetric reduction of prochiral ketones using a freshly prepared complex derived from NaBH4, 1/3 equiv of ZnCl2, and 1,2:5,6-di-O-isopropylidene-α-D-glucopyranose (1) gives an excess of the corresponding (S)-alcohols in substantial optical yields (28-69