Journal of Medicinal Chemistry p. 2001 - 2010 (1994)
Update date:2022-08-17
Topics:
Meltzer, Peter C.
Liang, Anna. Y.
Madras, Bertha. K.
Cocaine is a stimulant drug with a high abuse liability. Although it inhibits several monamine transporters in the mammalian brain, its primary mechanism of action has been ascribed to its inhibition of the dopamine transporter. The synthesis, characterization, and receptor binding properties of all eight isomers of a unique tropane analog, 2-carbomethoxy-3-
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